Data analysis, integration, and modelling

Project Summary

S1 will provide the consortium with standardized and established workflows for the analysis of next generation sequencing, metabolomics and proteomics data. In addition to the bioinformatic analysis and integration of different data types (Börries), the focus will be also on the statistical and integrative analysis of metabolomics data with the identification of metabolite biomarkers (Köttgen) as well as functional proteomics analyses based on human and murine biosamples (Schilling). Thus, S1 will use diverse high-dimensional data for the quantitative assessment of different immune responses, thereby promoting novel insights into immune escape mechanisms.