Oliver Schilling

Principal Investigator

Institute of Surgical Pathology
Medical Center University of Freiburg

Breisacher Straße 115a
79106 Freiburg

Current position

Heisenberg Professor (W3) for Translational Proteome Research, Institute of Surgical Pathology, Medical Center University of Freiburg

Academic training

1994 - 2000Studies in Biology in Münster, Germany, and Tours, France
(Diplom-Biologe and Licence de Biochimie)

Advanced academic qualifications

2014Habilitation (Venia Legendi) in Molecular Medicine, University of Freiburg
2004Doctorate (Dr. rer. nat.), University of Münster and European Molecular Biology Laboratory

Postgraduate positions

Since 2018Heisenberg Professor for Translational Proteome Research at the Institute of Surgical Pathology, University Freiburg Medical Center
2008 - 2018Research group leader, Institute of Molecular Medicine and Cell Research, University of Freiburg
2005 - 2008Postdoctoral fellow, University of British Columbia, Vancouver, Canada
2004Postdoctoral fellow, European Molecular Biology Laboratory
Hamburg/Heidelberg
2000 - 2004International PhD program, European Molecular Biology Laboratory
Hamburg/Heidelberg

Miscellaneous (Honors, Awards)

2017Heisenberg professorship of the DFG
2012 - 2017Starting Grant of the European Research Council ERC
2009 - 2014Emmy-Noether funding of the DFG

Publications listed in PubMed®

Publications (based on CRC1479 funding)

Kocsmár É, Schmid M, Cosenza-Contreras M, Kocsmár I, Föll M, Krey L, Barta BA, Rácz G, Kiss A, Werner M, Schilling O, Lotz G, Bronsert P. Proteome alterations in human autopsy tissues in relation to time after death. Cell Mol Life Sci. 2023 Apr 5;80(5):117. doi: 10.1007/s00018-023-04754-3.

Stillger MN, Chen CY, Lai ZW, Li M, Schäfer A, Pagenstecher A, Nimsky C, Bartsch JW, Schilling O. Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis. Cancer Cell Int. 2023 Mar 17;23(1):49. doi: 10.1186/s12935-023-02889-8.

Werner J, Bernhard P, Cosenza-Contreras M, Pinter N, Fahrner M, Pallavi P, Eberhard J, Bronsert P, Rückert F, Schilling O. Targeted and explorative profiling of kallikrein proteases and global proteome biology of pancreatic ductal adenocarcinoma, chronic pancreatitis, and normal pancreas highlights disease-specific proteome remodelling. Neoplasia. 2023 Feb;36:100871. doi: 10.1016/j.neo.2022.100871. Epub 2023 Jan 5.

Koistinen H, Kovanen RM, Hollenberg MD, Dufour A, Radisky ES, Stenman UH, Batra J, Clements J, Hooper JD, Diamandis E, Schilling O, Rannikko A, Mirtti T. The roles of proteases in prostate cancer. IUBMB Life. 2023 Jun;75(6):493-513. doi: 10.1002/iub.2700. Epub 2023 Jan 4.

 

Bernhard P, Feilen T, Rogg M, Fröhlich K, Cosenza-Contreras M, Hause F, Schell C, Schilling O. Proteome alterations during clonal isolation of established human pancreatic cancer cell lines. Cell Mol Life Sci. 2022 Oct 22;79(11):561. doi: 10.1007/s00018-022-04584-9.

Fröhlich K, Brombacher E, Fahrner M, Vogele D, Kook L, Pinter N, Bronsert P, Timme-Bronsert S, Schmidt A, Bärenfaller K, Kreutz C, Schilling O. Benchmarking of analysis strategies for data-independent acquisition proteomics using a large-scale dataset comprising inter-patient heterogeneity. Nat Commun. 2022 May 12;13(1):2622. doi: 10.1038/s41467-022-30094-0.

Pinter N, Glätzer D, Fahrner M, Fröhlich K, Johnson J, Grüning BA, Warscheid B, Drepper F, Schilling O, Föll MC. MaxQuant and MSstats in Galaxy Enable Reproducible Cloud-Based Analysis of Quantitative Proteomics Experiments for Everyone. J Proteome Res. 2022 May 3. doi: 10.1021/acs.jproteome.2c00051.