Oncogene-driven immune escape (OncoEscape)
Collaborative Research Centre 1479
The Collaborative Research Center (CRC) 1479 “Oncogene-driven immune escape” is a research consortium of clinical and basic tumor biologists and immunologist. Our CRC builds on the scientific hypothesis that oncogenic signalling and immune escape mechanisms are closely connected. This concept implies that targeting of oncogene-driven immune evasion could take treatment beyond palliative therapy towards cures for different types of cancer.
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Rahbari M, Gris-Oliver A, Ramadori P, Aicher D, Sia D, Malek NP, Loomba R, Bataller R, Llovet JM, Heikenwälder M. The versatile interplay between steatotic liver disease and liver cancer. Nat Rev Cancer. 2026 Apr 14. doi: 10.1038/s41568-026-00918-y. Epub ahead of print.
Gawron J, Czech M, Rückert T, Holzmüller V, Andreev G, Burk AC, Hartmann A, Chatterjee S, Andrieux G, Marquard FE, Baur AS, Stell AV, Krausz M, Braun LM, Osswald N, Melchinger W, Wertheimer T, Proano-Vasco AI, Maas-Bauer K, Schmitt-Graeff A, Boerries M, Köhler N, Ayuk FA, Schell C, Quante M, Zeiser R. Gastrin for the treatment of acute graft-versus-host disease of the stomach. Blood. 2026 Apr 9;147(15):1763-1778. doi: 10.1182/blood.2025031080.
Highlighted by: Chakraverty R. GVHD fails the acid test. Blood. 2026 Apr 9;147(15):1660-1662.
Maas-Bauer K, Meyer T, Yücel M, Garofalaki M, Koßmann S, Biavasco F, Lysandrou M, Waterhouse M, Feuchtinger T, Pfeifer D, Ingelfinger F, Wertheimer T, Duyster J, Ahn JS, Soiffer RJ, Finke J, Wäsch R, Spyridonidis A, Kim DDH, Wehr C, Zeiser R. Mutational landscape changes of AML in patients relapsing after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2026 Apr 3. doi: . Epub ahead of print.
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