Bertram Bengsch

Principal Investigator

Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases
Medical Center University of Freiburg

Hugstetter Straße 55
79106 Freiburg

Current position

Heisenberg Professor, Group leader and Section head for Translational Systems Immunology in Hepatogastroenterology, Clinic of Internal Medicine II, Medical Center University of Freiburg

Academic training

2002 - 2008Study of Medicine in Freiburg with electives in London, GB, and Philadelphia, USA

Advanced academic qualifications

2013PhD Dissertation (Faculty of Biology & SGBM), University of Freiburg
2008MD Dissertation, Faculty of Medicine, University of Freiburg

Postgraduate Positions

Since 2020Heisenberg Professor and Section Head of Translational Hepatogastroenterology, Clinic for Internal Medicine II, University Medical Center Freiburg
Since 10/17Group leader, Department of Medicine II, Freiburg
2014 - 2017Postdoctorate (DFG fellowship), Institute for Immunology & Parker Institute for Cancer Immunotherapy (Prof. E.J. Wherry), University of Pennsylvania, USA
2009 - 2014Clinical and research fellow, Department of Medicine II, University Hospital Freiburg

Miscellaneous (Honors, Awards)

2020Heisenberg Professorship (German Research Foundation)
2017 - 2019EXCEL Fellowship for Clinician Scientists, Faculty of Medicine, Freiburg
2016Postdoc scholarship award, Keystone meeting Q8 “Immunometabolism in Immune Function and Inflammatory Disease”
2014 - 2016Postdoctoral research fellowship of the German Research Foundation
2012MSD stipend for young clinician scientists (Hepatology / HIV)
2009 – 2013Spemann Graduate School of Biology & Medicine (SGBM) MD, PhD Scholarship
2008Ismar-Boas Prize –Prize (DGVS) for excellent medical thesis.
2006 & 2007Prize for distinguished dedication to academic Teaching, 2006-2007 (Medical Faculty Freiburg, Project „Cicil“), and Media Prize 2006 (University of Freiburg)

Publications listed in PubMed®

Publications (based on CRC1479 funding)

Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Sagar, Buescher JM, Pearce EJ, Pearce EL. Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment. Nat Commun. 2024 Jan 11;15(1):451. doi: 10.1038/s41467-024-44689-2.

Edwards-Hicks J, Apostolova P, Buescher JM, Maib H, Stanczak MA, Corrado M, Klein Geltink RI, Maccari ME, Villa M, Carrizo GE, Sanin DE, Baixauli F, Kelly B, Curtis JD, Haessler F, Patterson A, Field CS, Caputa G, Kyle RL, Soballa M, Cha M, Paul H, Martin J, Grzes KM, Flachsmann L, Mitterer M, Zhao L, Winkler F, Rafei-Shamsabadi DA, Meiss F, Bengsch B, Zeiser R, Puleston DJ, O’Sullivan D, Pearce EJ, Pearce EL. Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function. Nat Immunol. 2023 Mar;24(3):516-530. doi: 10.1038/s41590-023-01419-y. Epub 2023 Feb 2.

Barsch M, Salié H, Schlaak AE, Zhang Z, Hess M, Mayer LS, Tauber C, Otto-Mora P, Ohtani T, Nilsson T, Wischer L, Winkler F, Manne S, Rech A, Schmitt-Graeff A, Bronsert P, Hofmann M, Neumann-Haefelin C, Boettler T, Fichtner-Feigl S, van Boemmel F, Berg T, Rimassa L, Di Tommaso L, Saeed A, D’Alessio A, Pinato DJ, Bettinger D, Binder H, John Wherry E, Schultheiss M, Thimme R, Bengsch B. T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma. J Hepatol. 2022 Aug;77(2):397-409. doi: 10.1016/j.jhep.2022.02.032. Epub 2022 Apr 1.